Research - Portfolio of Studies

Lakeside Healthcare Research and Innovation Unit

• Novo Nordisk Zeus - A research study to look at how ziltivekimab works compared to placebo in people with cardiovascular disease, chronic kidney disease and inflammation.
• Novartis Victorian - 1 Prevent - A randomized, double-blind, placebo-controlled multicenter study to evaluate the effect of inclisiran on preventing major adverse cardiovascular events in high-risk primary prevention patients
• Moderna NextCove - A randomized, observer-blind, active-controlled Phase 3 study to investigate the safety and immunogenicity and relative vaccine efficacy of mRNA-1283.222 administered as a booster dose compared with mRNA1273.222 in participants aged 12 years and older for the prevention of COVID-19.
• GSK RSV 0A=ADJ-012 - An extension and crossover vaccination study on the immune response and safety of a vaccine against respiratory syncytial virus given to adults 60 years of age and above who participated in RSV OA=ADJ-006 study. (Portfolio Studies)
• Moderna Mpower mPox - A clinical trial of an investigational mpox vaccine, mRNA-1769-P101 for adults ages 18�C49.
• Leo Pharma Adjust - Adjustable brodalumab dosage regimen compared with standard brodalumab treatment for 52 weeks in subjects with moderate-to-severe plaque psoriasis and ≥120 kg body weight. 
• Amgen Vesalius CV Study -  A study looking at the efficacy of the drug Evolocumab (Repatha) is at lowering LDL-C in patients at risk of having a cardiovascular event.
• GSK COPD PAS - A study looking at safety cardiovascular outcome data for two inhalers used in the management of COPD.
• Novavax 2019nCoV-302 - A vaccine study looking at the efficacy of the Novavax Covid-19 vaccine in Adults in preventing serious Covid-19 Illness.
• Valneva VLA2001-301 - A vaccine study looking at the efficacy of the Valneva Covid-19 vaccine in Adults in preventing serious Covid-19 Illness.
• GSK RSV 006 - A vaccine study looking at the efficacy of a RSV (Respiratory Syncytial Virus) vaccine within older adults living in the community in preventing RSV infection.
• AstraZeneca LOGOS study - An Asthma study looking at the effectiveness of new combined triple therapy inhaler in patients with inadequately controlled Asthma.
• Boehringer Ingelheim 0022 CKD Study - A study for Chronic Kidney Disease looking at a new therapy to improve Kidney Function.
• George Medicines GMRx2 - A clinical trial called GMRx2, single pill containing three widely used blood lowering drugs. Testing the efficacy and safety of GMRx2 compared to placebo for the treatment of hypertension.
• Moderna CMVictory - A phase 3 vaccine study. Testing a new investigational vaccine (mRNA-1647) for its safety and effectiveness in preventing CMV in healthy adult females.